SDAP 2.0
Structural Database of Allergenic Proteins
University of Texas Medical Branch Biochemistry & Molecular Biology · Est. 2001
Department of Biochemistry and Molecular Biology Sealy Center for Structural Biology Computational Biology About Us
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Bioinformatics Servers BLAST @ NCBI FASTA @ EMBL-EBI Peptide Match @ PIR ClustalW @ EMBL-EBI
About SDAP

Publications

SDAP-related peer-reviewed publications

SDAP All Allergens SDAP Food Allergens Submit New Allergen Contact Werner Braun
Alphabetical listing of allergens ABCDEFGHIJKLMNOPQRSTUVWXYZ
SDAP Publications
  • Liu J, Negi SS, Yang C, Zhou X, Schein CH, Braun W, Kim P. AllergenAI: a deep learning model predicting allergenicity based on protein sequence. BMC Bioinformatics. 2025 Nov 18;26(1):279. [Abstract] [Full Paper]
  • Negi SS, Schein CH, Braun W. The updated Structural Database of Allergenic Proteins (SDAP 2.0) provides 3D models for allergens and incorporated Bioinformatics Tools. J Allergy Clin Immunol Glob. 2023;2(4):100162. [Abstract] [Full Paper]
  • Schein CH, Negi SS, Braun W. Still SDAPing Along: 20 Years of the Structural Database of Allergenic Proteins. Front. Allergy 3:863172. doi: 10.3389/falgy.2022.863172. [PubMed] [Full Paper]
  • Negi SS, Goldblum R, Braun W, Horiuti TM. Design of peptides with high affinity binding to a monoclonal antibody as a basis for immunotherapy. Peptides. 145:170628, 2021. [PubMed] [Full Paper]
  • Dreskin SC, Koppelman SJ, Andorf S, Nadeau KC, Kalra A, Braun W, Negi SS, Chen X, Schein CH. The importance of the 2S albumins for allergenicity and cross-reactivity of peanuts, tree nuts, and sesame seeds. J Allergy Clin Immunol 147(4):1154–1163, 2021. [PubMed] [Full Paper]
  • Dreskin SC, Germinaro M, Reinhold D, Chen X, Vickery BP, Kulis M, Burks WA, Negi SS, Braun W, Chambliss JM, Eglite S, McNulty CMG. IgE binding to linear epitopes of Ara h 2 in peanut allergic preschool children undergoing oral Immunotherapy. Pediatr Allergy Immunol 30(8):817–823, 2020. [PubMed] [Full Paper]
  • Lu W, Negi SS, Schein CH, Maleki SJ, Hulburt BK, Braun W. Distinguishing allergens from non-allergenic homologues using Physical-Chemical Property (PCP) motifs. Mol Immunol 9:1–8, 2018. [PubMed] [Full Paper]
  • Negi SS, Braun W. Cross-React: a new structural bioinformatics method for predicting allergen cross-reactivity. Bioinformatics 33(7):1014–1020, 2017. [PubMed] [Full Paper]
  • Power TD, Ivanciuc O, Schein CH, Braun W. Assessment of 3D models for allergen research. Proteins 81(4):545–554, 2013. [PubMed] [Full Paper]
  • Ivanciuc O, Gendel SM, Power TD, Schein CH, Braun W. AllerML: markup language for allergens. Regul Toxicol Pharmacol 60(1):151–160, 2011. [PubMed] [Full Paper]
  • Schein CH, Ivanciuc O, Midoro-Horiuti T, Goldblum RM, Braun W. An Allergen Portrait Gallery: Representative Structures and an Overview of IgE Binding Surfaces. Bioinform Biol Insights 4:113–125, 2010. [PubMed] [Full Paper]
  • Ivanciuc O, Schein CH, Garcia TI, Oezguen N, Negi SS, Braun W. Structural analysis of linear and conformational epitopes of allergens. Regul Toxicol Pharmacol 54(3 Suppl):S11–S19, 2009. [PubMed] [Full Paper]
  • Ivanciuc O, Midoro-Horiuti T, Schein CH, Xie L, Hillman GR, Goldblum RM, Braun W. The property index PD predicts peptides that cross-react with IgE antibodies. Mol Immunol 46(5):873–883, 2009. [PubMed] [Full Paper]
  • Ivanciuc O, Garcia TI, Torres M, Schein CH, Braun W. Characteristic motifs for families of allergenic proteins. Mol Immunol 46(4):559–568, 2009. [PubMed] [Full Paper]
  • Oezguen N, Zhou B, Negi SS, Ivanciuc O, Schein CH, Labesse G, Braun W. Comprehensive 3D-modeling of allergenic proteins and amino acid composition of potential conformational IgE epitopes. Mol Immunol 45(14):3740–3747, 2008. [PubMed] [Full Paper]
  • Schein CH, Ivanciuc O, Braun W. Bioinformatics approaches to classifying allergens and predicting cross-reactivity. Immunol Allergy Clin North Am 27(1):1–27, 2007. [PubMed] [Full Paper]
  • Midoro-Horiuti T, Schein CH, Mathura V, Braun W, Czerwinski EW, Togawa A, Kondo Y, Oka T, Watanabe M, Goldblum RM. Structural basis for epitope sharing between group 1 allergens of cedar pollen. Mol Immunol 43(6):509–518, 2006. [PubMed] [Full Paper]
  • Schein CH, Ivanciuc O, Braun W. Common physical-chemical properties correlate with similar structure of the IgE epitopes of peanut allergens. J Agric Food Chem 53(22):8752–8759, 2005. [PubMed] [Full Paper]
  • Ivanciuc O, Oezguen N, Mathura VS, Schein CH, Xu Y, Braun W. Using Property Based Sequence Motifs and 3D Modeling to Determine Structure and Functional Regions of Proteins. Curr Med Chem 11(5):583–893, 2004. [PubMed]
  • Ivanciuc O, Mathura V, Midoro-Horiuti T, Braun W, Goldblum RM, Schein CH. Detecting Potential IgE-Reactive Sites on Food Proteins Using a Sequence and Structure Database, SDAP-Food. J Agric Food Chem 51(16):4830–4837, 2003. [PubMed] [Full Paper]
  • Ivanciuc O, Schein CH, Braun W. SDAP: Database and Computational Tools for Allergenic Proteins. Nucleic Acids Res 31(1):359–362, 2003. [PubMed] [Full Paper]
  • Ivanciuc O, Schein CH, Braun W. Data Mining of Sequences and 3D Structures of Allergenic Proteins. Bioinformatics 18(10):1358–1364, 2002. [PubMed] [Full Paper]
  • Midoro-Horiuti T, Mathura V, Schein CH, Braun W, Yu S, Watanabe M, Lee JC, Brooks EG, Goldblum RM. Major linear IgE epitopes of mountain cedar pollen allergen Jun a 1 map to the pectate lyase catalytic site. Mol Immunol 40(8):555–562, 2003. [PubMed] [Full Paper]
  • Venkatarajan MS, Braun W. New quantitative descriptors of amino acids based on multidimensional scaling of a large number of physical-chemical properties. J Mol Model 7:445–453, 2001. [Full Paper]
  • Zhu H, Schein CH, Braun W. MASIA: recognition of common patterns and properties in multiple aligned protein sequences. Bioinformatics 16(10):950–951, 2000. [PubMed] [Full Paper]
  • Soman KV, Midoro-Horiuti T, Ferreon JC, Goldblum RM, Brooks EG, Kurosky A, Braun W, Schein CH. Homology modeling and characterization of IgE binding epitopes of mountain cedar allergen Jun A 3. Biophys J 79(3):1601–1609, 2000. [PubMed] [Full Paper]
  • Midoro-Horiuti T, Goldblum RM, Kurosky A, Wood TG, Schein CH, Brooks EG. Molecular cloning of mountain cedar (Juniperus ashei) pollen major allergen, Jun a 1. J Allergy Clin Immunol 104(3 Pt 1):613–617, 1999. [PubMed] [Full Paper]